Lonsurf Dose Calculator – Dr. Allan Pereira

Inform BSA or Weight and Height

BSA (m2)

If BSA is provided, height and weight are not required.

If BSA is unknown, calculate it first using height and weight.

Height

If BSA is not provided, BSA will be calculated using the Mosteller formula.

Weight

Calculated BSA (Mosteller)

This is the BSA that will be used for dose table matching.

Renal function

Select creatinine clearance category to show the appropriate initial dosing table.

CrCl >=30 mL/minute

No initial dosage adjustment is necessary. Uses 35 mg/m2/dose BID table.

CrCl 15 to 29 mL/minute

Uses 20 mg/m2/dose BID table, with 15 mg/m2/dose BID reduction option.

Lonsurf dose options

Click any visible row to override the BSA-matched option. Dose values are based on the trifluridine component.

Lonsurf systemic results

	Morning	Night	Units
Selected dose	—	—	mg
15 mg tablets per dose	—	—	tablets
20 mg tablets per dose	—	—	tablets
Total daily dose	—		mg/day
Total 15 mg tablets per 28-day cycle	—		15 mg tablets
Total 20 mg tablets per 28-day cycle	—		20 mg tablets

Schedule

2 weeks on/1 week off 1 week on / 1 week off

Prescription text (Lonsurf 20mg systemic)

Prescription text (Lonsurf 15mg systemic)

For adults only. Lonsurf tablet strengths assumed to be trifluridine/tipiracil 15mg/6.14mg and 20mg/8.19mg. This tool is for prescribing support and does not replace clinical judgment.